FMR1 Polyclonal Antibody

Reddot Biotech

FMR1 Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

FMR1

FMRP translational regulator 1

FMRP; fragile X mental retardation 1; fragile X mental retardation protein 1; FRAXA; POF; POF1; synaptic functional regulator FMR1; truncated FMRP

Rabbit

IgG

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Human, Mouse, Rat

-20°C

12352203