Bio-Connect
Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL [26628-22-8]

Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC043351
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSPTAN1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biotium
  • Product Name
    Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SPTAN1/3351
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID6709
  • Target name
    SPTAN1
  • Target description
    spectrin alpha, non-erythrocytic 1
  • Target synonyms
    alpha-fodrin; alpha-II spectrin; DEE5; EIEE5; epididymis secretory sperm binding protein; fodrin alpha chain; NEAS; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; SPTA2
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ13813
  • Protein Name
    Spectrin alpha chain, non-erythrocytic 1
  • Scientific Description
    Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203