![Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL [26628-22-8] Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-833.jpeg)
Fodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC043351
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSPTAN1
Overview
- SupplierBiotium
- Product NameFodrin / Alpha Spectrin II (SPTAN1) / NEAS(SPTAN1/3351), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSPTAN1/3351
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID6709
- Target nameSPTAN1
- Target descriptionspectrin alpha, non-erythrocytic 1
- Target synonymsalpha-fodrin; alpha-II spectrin; DEE5; EIEE5; epididymis secretory sperm binding protein; fodrin alpha chain; NEAS; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; SPTA2
- HostMouse
- IsotypeIgG2b
- Protein IDQ13813
- Protein NameSpectrin alpha chain, non-erythrocytic 1
- Scientific DescriptionSpectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203