More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Foretinib (GSK1363089,XL880)

Foretinib (GSK1363089,XL880)

Research Use Only
ORB181181
Biorbyt
CAS Number849217-64-7
Product group Chemicals
Molecular Weight632.65
Price on request
Packing Size
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Biorbyt
  • Product Name
    Foretinib (GSK1363089,XL880) [849217-64-7]
  • Delivery Days Customer
    16
  • CAS Number
    849217-64-7
  • Certification
    Research Use Only
  • Molecular Formula
    C34H34F2N4O6
  • Molecular Weight
    632.65
  • Scientific Description
    Foretinib (GSK1363089; XL880; EXEL-2880; GSK089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFRalpha/beta and Tie-2, and little activity to FGFR1 and EGFR.
  • SMILES
    O=C(NC1=CC=C(C(F)=C1)OC2=C3C=C(C(OCCCN4CCOCC4)=CC3=NC=C2)OC)C5(CC5)C(NC6=CC=C(C=C6)F)=O
  • UNSPSC
    12352200