Bio-Connect

Foretinib (phosphate)

HY-10338A
MedChem Express
Molecular Weight828.64
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Foretinib (phosphate)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C34H40F2N4O14P2
  • Molecular Weight
    828.64
  • Scientific Description
    Foretinib phosphate is an orally bioavailable small molecule with potential anti-tumor activity. Foretinib phosphate can selectively inhibit hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), thereby potentially inhibiting tumor angiogenesis, tumor cell proliferation and metastasis. Foretinib phosphate shows different anti-cancer activity from cabozantinib in lung cancer cells and has stronger inhibitory effects on targets such as MEK1/2, FER and AURKB [1] .
  • SMILES
    O=C(C1(CC1)C(NC2=CC=C(C(F)=C2)OC3=C4C=C(OC)C(OCCCN5CCOCC5)=CC4=NC=C3)=O)NC6=CC=C(C=C6)F.O=P(O)(O)O.O=P(O)(O)O
  • UNSPSC
    12352200