Foretinib (phosphate)
HY-10338A
Molecular Weight828.64
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameForetinib (phosphate)
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC34H40F2N4O14P2
- Molecular Weight828.64
- Scientific DescriptionForetinib phosphate is an orally bioavailable small molecule with potential anti-tumor activity. Foretinib phosphate can selectively inhibit hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), thereby potentially inhibiting tumor angiogenesis, tumor cell proliferation and metastasis. Foretinib phosphate shows different anti-cancer activity from cabozantinib in lung cancer cells and has stronger inhibitory effects on targets such as MEK1/2, FER and AURKB [1] .
- SMILESO=C(C1(CC1)C(NC2=CC=C(C(F)=C2)OC3=C4C=C(OC)C(OCCCN5CCOCC5)=CC4=NC=C3)=O)NC6=CC=C(C=C6)F.O=P(O)(O)O.O=P(O)(O)O
- UNSPSC12352200