Western blot analysis of extracts from A549, Hela and 3T3 cells using C-Fos Antibody.
FOS Antibody
CSB-PA042478
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFOS
Overview
- SupplierCusabio
- Product NameFOS Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2353
- Target nameFOS
- Target descriptionFos proto-oncogene, AP-1 transcription factor subunit
- Target synonymsactivator protein 1; AP-1; cellular oncogene c-fos; C-FOS; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; Fos proto-oncogene, AP-1 trancription factor subunit; G0/G1 switch regulatory protein 7; p55; proto-oncogene c-Fos
- HostRabbit
- IsotypeIgG
- Protein IDP01100
- Protein NameProto-oncogene c-Fos
- Scientific DescriptionNuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. Okazaki K., Sagata N.EMBO J. 14:5048-5059(1995) Zhang Y., Feng X.H., Derynck R.Nature 394:909-913(1998) Bossis G., Malnou C.E., Farras R. Mol. Cell. Biol. 25:6964-6979(2005)
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203