![FOXP3(3G3), CF640R conjugate, 0.1mg/mL [26628-22-8] FOXP3(3G3), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2016/12/BNUB0645-0-1.jpg)
FOXP3(3G3), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC400645
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityBovine, Human, Monkey, Mouse
TargetFOXP3
Overview
- SupplierBiotium
- Product NameFOXP3(3G3), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3G3
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID50943
- Target nameFOXP3
- Target descriptionforkhead box P3
- Target synonymsAIID; DIETER; forkhead box protein P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; PIDX; XPID
- HostMouse
- IsotypeIgG1
- Protein IDQ9BZS1
- Protein NameForkhead box protein P3
- Scientific DescriptionRecognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Monkey, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203