FR901379

TargetMol Chemicals

FR901379

1001

144371-88-0

Chemical

FR901379

C51H82N8O21S

1175.31

FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 ug/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.

3 years

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-20°

12352200