Framycetin (sulfate) [4146-30-9]
![Research Use Only](static/images/certificates/ruo.jpg)
HY-17624A
Overview
- SupplierMedChem Express
- Product NameFramycetin (sulfate) [4146-30-9]
- Delivery Days Customer10
- CAS Number4146-30-9
- CertificationResearch Use Only
- Estimated Purity98.0
- Molecular FormulaC23H52N6O25S3
- Molecular Weight908.88
- Scientific DescriptionFramycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 microM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 microM. Framycetin sulfate, a 5-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2].
- SMILESO=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.N[C@@H](C[C@H]1N)[C@@]([C@@H]([C@H]1O)O[C@@](O[C@H](CO)[C@H]2O[C@@]([C@@H]([C@@H](O)[C@@H]3O)N)([H])O[C@H]3CN)([H])[C@@H]2O)([H])O[C@H]([C@@H]([C@@H](O)[C@@H]4O)N)O[C@@H]4CN
- Storage Instruction2°C to 8°C
- UNSPSC12352200