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Framycetin (sulfate)

Research Use Only
HY-17624A
MedChem Express
CAS Number4146-30-9
Product group Chemicals
Estimated Purity98.0
Molecular Weight908.88
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Framycetin (sulfate) [4146-30-9]
  • Delivery Days Customer
    10
  • CAS Number
    4146-30-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C23H52N6O25S3
  • Molecular Weight
    908.88
  • Scientific Description
    Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 microM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 microM. Framycetin sulfate, a 5-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2].
  • SMILES
    O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.N[C@@H](C[C@H]1N)[C@@]([C@@H]([C@H]1O)O[C@@](O[C@H](CO)[C@H]2O[C@@]([C@@H]([C@@H](O)[C@@H]3O)N)([H])O[C@H]3CN)([H])[C@@H]2O)([H])O[C@H]([C@@H]([C@@H](O)[C@@H]4O)N)O[C@@H]4CN
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200