FREM1 Polyclonal Antibody

Reddot Biotech

FREM1 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

FREM1

FRAS1 related extracellular matrix 1

BNAR; C9orf143; C9orf145; C9orf154; extracellular matrix protein QBRICK; FRAS1-related extracellular matrix protein 1; MOTA; TILRR; TRIGNO2

Rabbit

IgG

This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Human, Mouse, Rat

-20°C

12352203