Frizzled 7 antibody

GeneTex

Frizzled 7 antibody

9

Western Blot

Research Use Only

Polyclonal

Unconjugated

FZD7

frizzled class receptor 7

frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; frizzled-7; fz-7; FzE3; hFz7

Rabbit

IgG

Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

Human, Mouse

2°C to 8°C,-20°C or -80°C

12352203