Frovatriptan (succinate)

MedChem Express

Frovatriptan (succinate) [158930-09-7]

10

158930-09-7

Research Use Only

C18H23N3O5

361.39

Frovatriptan succinate ((R)-Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and alpha1-adrenoceptor. Frovatriptan succinate has the potential for migraine research[1][2].

O=C(O)CCC(O)=O.O=C(C1=CC2=C(NC3=C2C[C@H](NC)CC3)C=C1)N

12352200