FSH-Receptor (Ovarian Marker) (FSHR/1400), CF640R conjugate, 0.1mg/mL [26628-22-8]

Biotium

FSH-Receptor (Ovarian Marker) (FSHR/1400), CF640R conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

FSHR/1400

0.1 mg/ml

Other Conjugate

CRYM

crystallin mu

DFNA40; ketimine reductase mu-crystallin; mu-crystallin homolog; NADP-regulated thyroid-hormone binding protein; THBP; thiomorpholine-carboxylate dehydrogenase

Mouse

IgG1

Follicle-stimulating hormone receptor

Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the beta subunit of FSH is involved in the binding of FSH to the receptor, the alpha subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203