Bio-Connect

FtsZ-IN-10

HY-W773487
MedChem Express
Molecular Weight352.79
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    FtsZ-IN-10
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C15H13ClN2O4S
  • Molecular Weight
    352.79
  • Scientific Description
    FtsZ-IN-10 is a bacterial division inhibitor that interferes with the normal assembly of FtsZ. FtsZ-IN-10 specifically binds to Bacillus subtilis FtsZ monomers, thereby affecting their polymerization behavior. FtsZ-IN-10 may also activate nucleotide-free archaeal FtsZ to form ordered polymers. FtsZ-IN-10 can hinder the localization of FtsZ in the Z ring and inhibit bacterial cell division. Chlorinated analogs of FtsZ-IN-10 show the ability to inhibit the growth of antibiotic-resistant clinical isolates such as Staphylococcus aureus and Enterococci [1] .
  • SMILES
    NC(C1=C(C=C(S1)C2=CC=C(C=C2)Cl)NC(CCC(O)=O)=O)=O
  • UNSPSC
    12352200