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ProductsBack/Fukutin antibody [N3C3-2]

Fukutin antibody [N3C3-2]

Research Use Only
GTX110302
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetFKTN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fukutin antibody [N3C3-2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2218
  • Target name
    FKTN
  • Target description
    fukutin
  • Target synonyms
    CMD1X; FCMD; fukutin; Fukuyama type congenital muscular dystrophy protein; LGMD2M; LGMDR13; MDDGA4; MDDGB4; MDDGC4; patient fukutin; ribitol-5-phosphate transferase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75072
  • Protein Name
    Fukutin
  • Scientific Description
    The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fukutin regulates tau phosphorylation and synaptic function: Novel properties of fukutin in neurons. Tsukui R et al., 2022 Feb, Neuropathology
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  • Fukutin Protein Participates in Cell Proliferation by Enhancing Cyclin D1 Expression through Binding to the Transcription Factor Activator Protein-1: An In Vitro Study. Okamura Y et al., 2021 Nov 10, Int J Mol Sci
    Read more