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Fura-FF AM
T37762
CAS Number348079-12-9
Product group Chemicals
Molecular Weight1023.811
Overview
- SupplierTargetMol Chemicals
- Product NameFura-FF AM
- Delivery Days Customer44
- CAS Number348079-12-9
- Category SupplierChemical
- Chemical NameFura-FF AM
- Molecular FormulaC43H43F2N3O24
- Molecular Weight1023.811
- Scientific DescriptionFura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt) . As fura-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce fura-FF. Fura-FF is a difluorinated derivative of the calcium indicator fura-2 . Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation. Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 uM, respectively). However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presence of a high calcium concentration. Low affinity calcium dyes, including fura-FF, are preferred for studying compartments with high concentrations of calcium, such as mitochondria, or in cell systems that have relatively low calcium buffering capacities, such as neuronal dendrites and spines.
- Shelf life instruction3 years
- SMILESCC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1cc2oc(cc2cc1OCCOc1c(F)c(F)ccc1N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c1ncc(o1)C(=O)OCOC(C)=O
- Storage Instruction-20°
- UNSPSC12352200