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Futibatinib

HY-100818
MedChem Express
CAS Number1448169-71-8
Product group Chemicals
Estimated Purity99.65
Molecular Weight418.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Futibatinib [1448169-71-8]
  • Delivery Days Customer
    10
  • CAS Number
    1448169-71-8
  • Estimated Purity
    99.65
  • Molecular Formula
    C22H22N6O3
  • Molecular Weight
    418.45
  • Scientific Description
    Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM) [1] [2] [3] .
  • SMILES
    O=C(C=C)N(C1)CC[C@@H]1N(N=C2C#CC3=CC(OC)=CC(OC)=C3)C4=C2C(N)=NC=N4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200