Futibatinib
HY-100818
CAS Number1448169-71-8
Product group Chemicals
Estimated Purity99.65
Molecular Weight418.45
Overview
- SupplierMedChem Express
- Product NameFutibatinib [1448169-71-8]
- Delivery Days Customer10
- CAS Number1448169-71-8
- Estimated Purity99.65
- Molecular FormulaC22H22N6O3
- Molecular Weight418.45
- Scientific DescriptionFutibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM) [1] [2] [3] .
- SMILESO=C(C=C)N(C1)CC[C@@H]1N(N=C2C#CC3=CC(OC)=CC(OC)=C3)C4=C2C(N)=NC=N4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200