FZD6 Polyclonal Antibody
RD76603A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetFZD6
Overview
- SupplierReddot Biotech
- Product NameFZD6 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID8323
- Target nameFZD6
- Target descriptionfrizzled class receptor 6
- Target synonymsfrizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; frizzled-6; FZ6; FZ-6; HFZ6; NDNC1; NDNC10; seven transmembrane helix receptor
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene represents a member of the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203