Bio-Connect

FZD6 Polyclonal Antibody

Research Use Only
RD76603A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetFZD6
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    FZD6 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8323
  • Target name
    FZD6
  • Target description
    frizzled class receptor 6
  • Target synonyms
    frizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; frizzled-6; FZ6; FZ-6; HFZ6; NDNC1; NDNC10; seven transmembrane helix receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene represents a member of the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203