G6PC Polyclonal Antibody

Reddot Biotech

G6PC Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.44 mg/ml

Unconjugated

G6PC1

glucose-6-phosphatase catalytic subunit 1

G6Pase; G-6-Pase; G6Pase-alpha; G6PC; G6PT; glucose-6-phosphatase alpha; glucose-6-phosphatase catalytic subunit 1; GSD1; GSD1a

Rabbit

IgG

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.

Human, Mouse, Rat

-20°C

12352203