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Gabexate (mesylate) (Standard)

HY-B0385R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Gabexate (mesylate) (Standard) [56974-61-9]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 microM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 microM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-kappaB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation [1] [2] [3] [4] .
  • UNSPSC
    41116135