Western Blot analysis of Human fetal brain tissue using GAD1 Polyclonal Antibody at dilution of 1:571
Western Blot analysis of Human fetal brain tissue using GAD1 Polyclonal Antibody at dilution of 1:571
GAD1 Polyclonal Antibody
E-AB-12441
Product group Antibodies
Overview
- SupplierElabscience
- Product NameGAD1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.7mg/ml
- Scientific DescriptionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
- UNSPSC12352203