GADD45A Polyclonal Antibody
RD81440A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGADD45A
Overview
- SupplierReddot Biotech
- Product NameGADD45A Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1647
- Target nameGADD45A
- Target descriptiongrowth arrest and DNA damage inducible alpha
- Target synonymsDDIT1; DDIT-1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; GADD45; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203