The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA526376(GADD45B Antibody) at dilution 1/40. (Original magnification: x200)
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA526376(GADD45B Antibody) at dilution 1/40. (Original magnification: x200)
GADD45B Antibody
CSB-PA526376
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetGADD45B
Overview
- SupplierCusabio
- Product NameGADD45B Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4616
- Target nameGADD45B
- Target descriptiongrowth arrest and DNA damage inducible beta
- Target synonymsGADD45BETA; growth arrest and DNA damage-inducible protein GADD45 beta; MYD118; myeloid differentiation primary response protein MyD118; negative growth regulatory protein MyD118
- HostRabbit
- IsotypeIgG
- Protein IDO75293
- Protein NameGrowth arrest and DNA damage-inducible protein GADD45 beta
- Scientific DescriptionThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203