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GADD45B Protein, Human, Recombinant (His)

Research Use Only
TMPJ-00700
TargetMol Chemicals
Molecular Weight24 KDa (reducing condition)
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GADD45B Protein, Human, Recombinant (His)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    24 KDa (reducing condition)
  • Scientific Description
    Growth Arrest and DNA Damage-Inducible Protein GADD45 beta (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It may serve as a possible therapeutic target.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200