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Galectin 3 antibody

GTX125897
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLGALS3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Galectin 3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Sandwich ELISA: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3958
  • Target name
    LGALS3
  • Target description
    galectin 3
  • Target synonyms
    35 kDa lectin; advanced glycation end-product receptor 3; carbohydrate-binding protein 35; CBP35; epididymis secretory sperm binding protein; GAL3; galactose-specific lectin 3; GALBP; galectin-3; GALIG; IgE-binding protein; L31; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3; LGALS2; MAC2; MAC-2 antigen
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP17931
  • Protein Name
    Galectin-3
  • Scientific Description
    This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Thyroid cancer diagnosis by Raman spectroscopy. Sbroscia M et al., 2020 Aug 7, Sci Rep
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  • Helicobacter pylori induces intracellular galectin-8 aggregation around damaged lysosomes within gastric epithelial cells in a host O-glycan-dependent manner. Li FY et al., 2019 Feb 1, Glycobiology
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  • Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells. Lin GL et al., 2017, PLoS One
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  • Secretome protein signature of human pancreatic cancer stem-like cells. Brandi J et al., 2016 Mar 16, J Proteomics
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  • Proteomic analysis of rhein-induced cyt: ER stress mediates cell death in breast cancer cells. Huang HJ et al., 2014 Dec, Mol Biosyst
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  • Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin. Chemaly ER et al., 2013 Nov 1, J Physiol
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  • High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease. Chen JY et al., 2013 Nov, J Nutr Biochem
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