Gambogenic acid [173932-75-7]
S9031
CAS Number173932-75-7
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameGambogenic acid [173932-75-7]
- Delivery Days Customer9
- CAS Number173932-75-7
- CertificationResearch Use Only
- Scientific DescriptionGambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.
- UNSPSC12352200