gamma-Amanitin [21150-23-2]

MedChem Express

gamma-Amanitin [21150-23-2]

10

21150-23-2

Research Use Only

Monoclonal

90.0

C39H54N10O13S

902.97

gamma-Amanitin an ADC cytotoxin and isolated from the mushroom. gamma-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. gamma-Amanitin shows similar effects to alpha-Amanitin and beta-Amanitin. gamma-Amanitin competitively binds to monoclonal antibody (mAb), with an IC50 of 163.1 ng/mL. gamma-Amanitin is toxic to a variety of cells[1][2][3].

O=[S](C[C@H](NC(CNC1=O)=O)C(N[C@H](C2=O)CC(N)=O)=O)C(N3)=C(C[C@@H](C(NCC(N[C@H]1[C@@H](C)CC)=O)=O)NC([C@@H](NC([C@H](C4)N2C[C@@H]4O)=O)[C@@H](C)[C@@H](O)C)=O)C(C3=C5)=CC=C5O

-20°C

41115800