Gamma-Mangostin (Standard)

MedChem Express

Gamma-Mangostin (Standard) [31271-07-5]

9

Research Use Only

Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer [2] . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes ( IC 50 =3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A ( IC 50 =0.32 microM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes [1] [2] [3] [4] [5] .

41116135