gamma-Secretase modulator 13 [1353570-40-7]

MedChem Express

gamma-Secretase modulator 13 [1353570-40-7]

10

1353570-40-7

Research Use Only

C22H23FN6S

422.52

gamma-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid beta-peptide Abeta42 with an IC50 value of 163 nM. gamma-Secretase modulator 13 can be used in the study of Alzheimers disease[1].

FC1=C(N2C=NC(C)=C2)C=CC(C3=CSC(NC4=C5C(CCCC5)=NN4CC)=N3)=C1

12352200