
GAS6 Protein, Human, Recombinant (His)
TMPY-04999
Estimated Purity> 99.9%
Product group Chemicals
Molecular Weight72.7 KDa (Predicted), 80-90 KDa (Reducing conditions)
Overview
- SupplierTargetMol Chemicals
- Product NameGAS6 Protein, Human, Recombinant (His)
- Delivery Days Customer16
- CertificationResearch Use Only
- Estimated Purity> 99.9%
- Molecular Weight72.7 KDa (Predicted), 80-90 KDa (Reducing conditions)
- Scientific DescriptionGAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.
- Storage Instruction-20°C
- UNSPSC12352200