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GAT107 [1476807-74-5]
T27404
Overview
- SupplierTargetMol Chemicals
- Product NameGAT107 [1476807-74-5]
- Delivery Days Customer9
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameGAT107
- Molecular FormulaC18H17BrN2O2S
- Molecular Weight405.31
- Scientific DescriptionGAT107 is a novel and potent alpha7 nicotinic cholinergic receptor modifier agonist and modulator with anti-inflammatory activity that reverses injury perception in a mouse model of neuropathic pain.
- Shelf life instruction3 years
- SMILESS(N)(=O)(=O)C=1C=C2[C@@]3([C@]([C@H](NC2=CC1)C4=CC=C(Br)C=C4)(CC=C3)[H])[H]
- Storage Instruction-20°C
- UNSPSC12352200
References
- Gauthier AG, et al. GAT107-mediated alfa7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation. Redox Biol. 2023 Apr;60:102614.Read more