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CgoaEWY7K4KEYvPlAAAAAJgwYNI604.png
CgoaEWY7K4KEYvPlAAAAAJgwYNI604.png
CgoaEWY7K4KEYvPlAAAAAJgwYNI604.png

GAT107 [1476807-74-5]

Research Use Only
T27404
TargetMol Chemicals
Molecular Weight405.31
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GAT107 [1476807-74-5]
  • Delivery Days Customer
    9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GAT107
  • Molecular Formula
    C18H17BrN2O2S
  • Molecular Weight
    405.31
  • Scientific Description
    GAT107 is a novel and potent alpha7 nicotinic cholinergic receptor modifier agonist and modulator with anti-inflammatory activity that reverses injury perception in a mouse model of neuropathic pain.
  • Shelf life instruction
    3 years
  • SMILES
    S(N)(=O)(=O)C=1C=C2[C@@]3([C@]([C@H](NC2=CC1)C4=CC=C(Br)C=C4)(CC=C3)[H])[H]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Gauthier AG, et al. GAT107-mediated alfa7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation. Redox Biol. 2023 Apr;60:102614.
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