GBA Polyclonal Antibody

Reddot Biotech

GBA Polyclonal Antibody

5

1.56 mg/ml

GBA

glucosylceramidase beta

acid beta-glucosidase; alglucerase; beta-GC; beta-glucocerebrosidase; cholesterol glucosyltransferase; cholesteryl-beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; GBA1; GCB; GLUC; glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase-like protein; imiglucerase; lysosomal acid GCase; lysosomal acid glucosylceramidase; lysosomal glucocerebrosidase; SGTase

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

-20°C

12352203