GBR 12783 (dihydrochloride)

MedChem Express

GBR 12783 (dihydrochloride) [67469-75-4]

5

67469-75-4

99.14

C28H34Cl2N2O

485.49

GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [ 3 H]dopamine uptake by rat and mice striatal synaptosomes with IC 50 s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats [1] [2] .

N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(C/C=C/C4=CC=CC=C4)CC1.Cl.Cl

-20°C

12352200