GBR 12935

MedChem Express

GBR 12935 [76778-22-8]

10

76778-22-8

Research Use Only

C28H34N2O

414.58

GBR 12935 is a potent, and selective dopamine reuptake inhibitor, with the binding constant (K d ) of 1.08 nM in COS-7 cells. GBR 12935 stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 also prevents the d-Fenfluramine-induced head-twitch response in mice [1] [2] [3] [4] .

N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(CCCC4=CC=CC=C4)CC1

12352200