GBR-12935 maleate

TargetMol Chemicals

GBR-12935 maleate

72

1349767-56-1

Chemical

GBR-12935 maleate

C32H38N2O5

530.665

GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. (Source: http://en.wikipedia.org/wiki/GBR-12935).

3 years

OC(=O)\C=C/C(O)=O.C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1

-20°

12352200