Gcase activator 2 [2759897-35-1]

TargetMol Chemicals

Gcase activator 2 [2759897-35-1]

16

Research Use Only

C21H24N4O2

364.44

GCase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is a beta-Glucocerebrosidase (GCase) activator (EC50 = 3.8 microM) that induces GCase dimerization (both K-type and V-type) and demonstrates low metabolic clearance in humans and mice [1].

CN1C=2C(C=C1C3CCN(C(C)=O)CC3)=NC(=CN2)C4=CC=C(OC)C=C4

-20°C

51202000