
FACS analysis of 4% PFA-fixed mouse spleen cells using GTX04587 GCN2 (phospho Thr899) antibody. Green : Primary antibody Orange : Isotype control Blue : Secondary antibody only Black : Unlabeled cells Permeabilization : 0.1% PBST Dilution : 1:50
GCN2 (phospho Thr899) antibody
GTX04587
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetEIF2AK4
Overview
- SupplierGeneTex
- Product NameGCN2 (phospho Thr899) antibody
- Delivery Days Customer9
- Antibody SpecificityThis phosphorylation site is homologous to Thr898 in Mouse and Thr899 in Rat.
- Application Supplier NoteWB: 1:300-1:5000. FACS: 1:20-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID440275
- Target nameEIF2AK4
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 4
- Target synonymseIF-2-alpha kinase GCN2; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; PVOD2
- HostRabbit
- IsotypeIgG
- Protein IDQ9P2K8
- Protein NameeIF-2-alpha kinase GCN2
- Scientific DescriptionThis gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203