Bio-Connect

GDC-2394 [2238822-07-4]

HY-148258
MedChem Express
CAS Number2238822-07-4
Product group Chemicals
Estimated Purity99.87
Molecular Weight431.51
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GDC-2394 [2238822-07-4]
  • Delivery Days Customer
    10
  • CAS Number
    2238822-07-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.87
  • Molecular Formula
    C20H25N5O4S
  • Molecular Weight
    431.51
  • Scientific Description
    GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1beta with IC50s of 0.4 microM (human IL-1beta) and 0.1 microM (mouse IL-1beta). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation[1][2].
  • SMILES
    O=S(C1=C2OC[C@@H](NC)CN2N=C1)(NC(NC3=C4CCCC4=CC5=C3CCC5)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12131703