Gefapixant (citrate)

MedChem Express

Gefapixant (citrate)

10

Research Use Only

99.23

C20H27N5O11S

545.52

Gefapixant citrate is an orally active and potent purinergic P2X3 receptor ( P2X3R ) antagonist, with IC 50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis [1] [2] [3] .

O=C(CC(C(O)=O)(CC(O)=O)O)O.O=S(N)(C1=C(OC)C=C(C(C)C)C(OC2=CN=C(N)N=C2N)=C1)=O

-20°C,2°C to 8°C

12352200