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Gefitinib-based PROTAC 3

S0070
Selleck Chemicals
CAS Number2230821-27-7
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Gefitinib-based PROTAC 3 [2230821-27-7]
  • Delivery Days Customer
    9
  • CAS Number
    2230821-27-7
  • Estimated Purity
    ...
  • Scientific Description
    Gefitinib-based PROTAC 3 which conjugates an EGFR binding element to a VHL ligand via a linker induces degradation of EGFR and mutants with DC50 of 11.7 nM and 22.3 nM in HCC827(Exon 19 del) and H3255 (L858R) cells, respectively.
  • UNSPSC
    51202000

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