Gefitinib-d6 [1228664-49-0]
HY-50895S1
CAS Number1228664-49-0
Product group Chemicals
Molecular Weight452.94
Overview
- SupplierMedChem Express
- Product NameGefitinib-d6 [1228664-49-0]
- Delivery Days Customer10
- CAS Number1228664-49-0
- CertificationResearch Use Only
- Molecular FormulaC22H18D6ClFN4O3
- Molecular Weight452.94
- Scientific DescriptionGefitinib-d6 is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
- SMILESCOC1=CC2=C(C=C1OC([2H])(C([2H])(C([2H])(N3CCOCC3)[2H])[2H])[2H])C(NC4=CC=C(C(Cl)=C4)F)=NC=N2
- Storage InstructionSee Manual
- UNSPSC12352200