Gefitinib impurity 2

MedChem Express

Gefitinib impurity 2 [246512-44-7]

5

246512-44-7

99.56

C15H23N3O4

309.366

Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy . Gefitinib has antitumour activity [1] [2] .

O=C(N)C1=CC(OCCCN2CCOCC2)=C(OC)C=C1N

-20°C,2°C to 8°C

12352200