
IHC analysis of mouse brain cultures using GTX85454 GFAP antibody. Red : Primary antibody Blue : DAPI
GFAP antibody
GTX85454
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
Overview
- SupplierGeneTex
- Product NameGFAP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:2000. IHC: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID2670
- Target nameGFAP
- Target descriptionglial fibrillary acidic protein
- Target synonymsALXDRD; glial fibrillary acidic protein
- HostChicken
- IsotypeIgY
- Protein IDP14136
- Protein NameGlial fibrillary acidic protein
- Scientific DescriptionThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.Read more
- Reprogramming astrocytic NDRG2/NF-kappaB/C3 signaling restores the diabetes-associated cognitive dysfunction.Read more
- Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment.Read more
- In situ microwave fixation provides an instantaneous snapshot of the brain metabolome.Read more
- PERK-STING-RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis-associated encephalopathy.Read more
- TNFalpha-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation. Huang WY et al., 2022 Feb 2, J NeuroinflammationRead more
- High throughput screening of novel AAV capsids identifies variants for transduction of adult NSCs within the subventricular zone. Kremer LPM et al., 2021 Dec 10, Mol Ther Methods Clin DevRead more
- micro-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. Gao H et al., 2021 Jul, Mol NeurobiolRead more
- NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation. Zhang Y et al., 2021 Feb, J Mol HistolRead more
- Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice. Fan Z et al., 2020 Dec, Neurosci BullRead more