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IHC analysis of mouse brain cultures using GTX85454 GFAP antibody. Red : Primary antibody Blue : DAPI

GFAP antibody

GTX85454

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetGFAP

Overview

Supplier
GeneTex
Product Name
GFAP antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:2000. IHC: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
2 mg/ml
Conjugate
Unconjugated
Gene ID2670
Target name
GFAP
Target description
glial fibrillary acidic protein
Target synonyms
ALXDRD, glial fibrillary acidic protein
Host
Chicken
Isotype
IgY
Protein IDP14136
Protein Name
Glial fibrillary acidic protein
Scientific Description
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Reactivity
Human, Mouse, Rat
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Wei H, Zhen L, Wang S, et al. Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice. J Neuroinflammation. 2023,20(1):264. doi: 10.1186/s12974-023-02942-3
Read this paper
Jiang T, Li Y, He S, et al. Reprogramming astrocytic NDRG2/NF-κB/C3 signaling restores the diabetes-associated cognitive dysfunction. EBioMedicine. 2023,93:104653. doi: 10.1016/j.ebiom.2023.104653
Read this paper
Li Q, Zhao Y, Guo H, et al. Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment. Autophagy. 2023,19(10):2639-2656. doi: 10.1080/15548627.2023.2213984
Read this paper
Juras JA, Webb MB, Young LEA, et al. In situ microwave fixation provides an instantaneous snapshot of the brain metabolome. Cell Rep Methods. 2023,3(4):100455. doi: 10.1016/j.crmeth.2023.100455
Read this paper
Xiaofeng G, You W, Qi J, et al. PERK-STING-RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis-associated encephalopathy. CNS Neurosci Ther. 2023,29(4):1178-1191. doi: 10.1111/cns.14095
Read this paper
Huang WY, Lai YL, Liu KH, et al. TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation. J Neuroinflammation. 2022,19(1):29. doi: 10.1186/s12974-022-02406-0
Read this paper
Kremer LPM, Cerrizuela S, Dehler S, et al. High throughput screening of novel AAV capsids identifies variants for transduction of adult NSCs within the subventricular zone. Mol Ther Methods Clin Dev. 2021,23:33-50. doi: 10.1016/j.omtm.2021.07.001
Read this paper
Gao H, Zhang Y, Li Y, et al. μ-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. Mol Neurobiol. 2021,58(7):3061-3070. doi: 10.1007/s12035-021-02286-0
Read this paper
Zhang Y, Gao H, Li N, et al. NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation. J Mol Histol. 2021,52(1):101-111. doi: 10.1007/s10735-020-09927-z
Read this paper
Fan Z, Zhang Z, Zhao S, et al. Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice. Neurosci Bull. 2020,36(12):1513-1523. doi: 10.1007/s12264-020-00587-3
Read this paper

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GFAP antibody

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