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IHC analysis of mouse brain cultures using GTX85454 GFAP antibody. Red : Primary antibody Blue : DAPI
IHC analysis of mouse brain cultures using GTX85454 GFAP antibody. Red : Primary antibody Blue : DAPI
IHC analysis of mouse brain cultures using GTX85454 GFAP antibody. Red : Primary antibody Blue : DAPI

GFAP antibody

GTX85454
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
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Overview

  • Supplier
    GeneTex
  • Product Name
    GFAP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:2000. IHC: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2670
  • Target name
    GFAP
  • Target description
    glial fibrillary acidic protein
  • Target synonyms
    ALXDRD; glial fibrillary acidic protein
  • Host
    Chicken
  • Isotype
    IgY
  • Protein IDP14136
  • Protein Name
    Glial fibrillary acidic protein
  • Scientific Description
    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.
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  • Reprogramming astrocytic NDRG2/NF-kappaB/C3 signaling restores the diabetes-associated cognitive dysfunction.
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  • Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment.
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  • In situ microwave fixation provides an instantaneous snapshot of the brain metabolome.
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  • PERK-STING-RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis-associated encephalopathy.
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  • TNFalpha-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation. Huang WY et al., 2022 Feb 2, J Neuroinflammation
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  • High throughput screening of novel AAV capsids identifies variants for transduction of adult NSCs within the subventricular zone. Kremer LPM et al., 2021 Dec 10, Mol Ther Methods Clin Dev
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  • micro-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. Gao H et al., 2021 Jul, Mol Neurobiol
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  • NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation. Zhang Y et al., 2021 Feb, J Mol Histol
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  • Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice. Fan Z et al., 2020 Dec, Neurosci Bull
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