Bio-Connect

GFAP Antibody: APC

ORB150524
Biorbyt
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
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Overview

  • Supplier
    Biorbyt
  • Product Name
    GFAP antibody
  • Delivery Days Customer
    16
  • Application Supplier Note
    1 microg/ml of SMC-441 was sufficient for detection of GFAP in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Applications Supplier
    WB (1:1000) ICC, IF, IHC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N206A/8 (Formerly sold as S206A-8)
  • Concentration
    1 mg/ml
  • Conjugate
    APC (Allophycocyanin)
  • Gene ID2670
  • Target name
    GFAP
  • Target description
    glial fibrillary acidic protein
  • Target synonyms
    ALXDRD; glial fibrillary acidic protein
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP14136
  • Protein Name
    Glial fibrillary acidic protein
  • Scientific Description
    Mouse monoclonal to GFAP (APC). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia..
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    See Manual
  • UNSPSC
    12352203