GFAP Antibody: RPE
ORB150530
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGFAP
Overview
- SupplierBiorbyt
- Product NameGFAP antibody
- Delivery Days Customer16
- Application Supplier Note1 microg/ml of SMC-441 was sufficient for detection of GFAP in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- Applications SupplierWB (1:1000) ICC, IF, IHC, WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDN206A/8 (Formerly sold as S206A-8)
- Concentration1 mg/ml
- ConjugateRPE
- Gene ID2670
- Target nameGFAP
- Target descriptionglial fibrillary acidic protein
- Target synonymsALXDRD; glial fibrillary acidic protein
- HostMouse
- IsotypeIgG1
- Protein IDP14136
- Protein NameGlial fibrillary acidic protein
- Scientific DescriptionMouse monoclonal to GFAP (RPE). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia..
- ReactivityHuman, Mouse, Rat
- Storage InstructionSee Manual
- UNSPSC12352203