GFRA2 Polyclonal Antibody
RD253256A
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetGFRA2
Overview
- SupplierReddot Biotech
- Product NameGFRA2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID2675
- Target nameGFRA2
- Target descriptionGDNF family receptor alpha 2
- Target synonymsGDNF family receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFRB; GDNFR-beta; GFR-alpha 2; glial cell line derived neurotrophic factor receptor, beta; neurturin receptor alpha; NRTNR-ALPHA; NTNRA; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionGlial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203