Gilteritinib-d8 [2377109-74-3]

TargetMol Chemicals

Gilteritinib-d8 [2377109-74-3]

16

Research Use Only

C29H36D8N8O3

560.76

Gilteritinib-d8 is a deuterated compound of Gilteritinib. Gilteritinib has a CAS number of 1254053-43-4. Gilteritinib is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 Clinicalal trials for acute myeloid leukemia.

[2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(C2CCN(C3C=CC(NC4C(C(N)=O)=NC(CC)=C(NC5CCOCC5)N=4)=CC=3OC)CC2)C1([2H])[2H]

-20°C

12352200