Gilvocarcin M [77879-89-1]

TargetMol Chemicals

Gilvocarcin M [77879-89-1]

44

77879-89-1

Chemical

Research Use Only

Gilvocarcin M

C26H26O9

482.485

Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 microg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 microg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400 mg/kg. Gilvocarcin M intercalates into bacteriophage PM2 DNA. It is toxic to rats with an intravenous LD50 value of 450 mg/kg.

3 years

[H][C@]1(O[C@@H]([C@H](O)[C@H]1O)c1ccc(O)c2c(OC)cc3c(oc(=O)c4cc(C)cc(OC)c34)c12)[C@@H](C)O

-20°C

12352200