GITR/TNFRSF18 Polyclonal Antibody

Reddot Biotech

GITR/TNFRSF18 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

TNFRSF18

TNF receptor superfamily member 18

activation-inducible TNFR family receptor; AITR; CD357; ENERGEN; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; tumor necrosis factor receptor superfamily member 18

Rabbit

IgG

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Mouse

-20°C

12352203