GK718

MedChem Express

GK718

14

Research Use Only

C26H30Cl2N4O3

517.45

GK718 is a HDAC1/3 inhibitor (IC50: 259 and 139 nM respectively). GK718 increased acetylated histone H3 level in cells. GK718 inhibits Bleomycin (HY-108345) induced pulmonary fibrosis in mice[1].

O=C([C@@H]1NCCC1)NCC2=CC=C(OCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3)C=C2.Cl.Cl

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