GLA Polyclonal Antibody
RD267013A
ApplicationsImmunoFluorescence, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetGLA
Overview
- SupplierReddot Biotech
- Product NameGLA Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2717
- Target nameGLA
- Target descriptiongalactosidase alpha
- Target synonymsagalsidase alfa; alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosylgalactosylglucosylceramidase GLA; melibiase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203